Medical Director

Title: Medical Director ABOUT THE COMPANY QurAlis is a clinical-stage biotechnology company developing breakthrough precision medicines for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with genetically validated targets. QurAlis is trailblazing the path to conquering amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases with genetically validated targets with next-generation precision medicines. QurAlis’ proprietary platforms and unique biomarkers enable the design and development of drugs that act directly on disease-causing genetic alterations. Founded by an internationally recognized team of neurodegenerative biologists from Harvard Medical School and Harvard University, QurAlis is advancing a deep pipeline of antisense oligonucleotides and small molecule programs including addressing sub-forms of ALS that account for the majority of ALS patients. SUMMARY OF POSITION Reporting to the CMO, in this newly created position, we are seeking a motivated experienced Quralis Medical Director. Primary Job Responsibilities: • Support clinical programs (up to 2) by developing and/or contributing to, with a cross functional team, Clinical Development plans and study protocols • Participate in clinical trial team meetings (internal and external) for both ongoing studies; help with planning and development of future clinical trials • Responsible for oversight of CRO medical monitor(s); provide medical expertise on ALS and our investigational product; ongoing risk: benefit evaluation, at a study, program and portfolio level • Contribute and review (medical and safety expertise) in the development of Informed Consent Forms (ICFs), Case Report Forms (CRF), CRF completion guidelines and edit specifications, statistical analysis plan (SAP), Serious Adverse Events (SAE) forms and reports (assist with risk: benefit review), and more • Participate in ongoing, QurAlis led, data reviews • Engage with study Investigators (the Sponsor voice) and program/ALS KOLs • Other medical/clinical development activities, as identified by the CMO and/or clinical trial team Primary Job Requirements: • MD with Board Certification in a relevant discipline such as, internal medicine, neurology etc. • Subspecialty Endocrine/GI/Renal, a plus • Combination of at least 5-10 years of clinical academic research and 3-5yrs industry drug development experience (neuromuscular diseases such as ALS a plus, but not necessary) • Experience designing, and developing, or overseeing others in design and development of clinical studies and cross-functional initiatives • Willingness to work in new drug development areas • Strategic/creative thinker/results oriented • Excels in a multi-project, fast-track team-oriented environment. • Strong interpersonal, communication, influencing, problem solving, skills Please send resume with cover letter to anna.beck@quralis.com QurAlis is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. QurAlis will make reasonable accommodations for